Prof. Dr. med. Sebastian Ley

1994 – 2001          Studium der Humanmedizin an der Johannes Gutenberg-Universität Mainz

2001                     Promotion Universität Mainz

2001 – 2008          Facharztausbildung Universitätsklinik Mainz, Deutsches Krebs Forschungszentrum   Heidelberg, Universitätsklinik Heidelberg (Radiologie)

2008-2010            Oberarzt Radiologie Universität Heidelberg

2009                     Habilitation (Lehrbefugnis für Radiologie) Universität Heidelberg

2010 – 2012          Associate Professor at the Department of Radiology, Toronto General Hospital,        Toronto, Canada (Cardiothoracic Division)

2011                     Q3-Ausbilder Herz-MRT und Herz-CT der Deutschen Röntgengesellschaft

2011                     European Diploma in Cardiac Radiology

2011                     Schwerpunkt Kinderradiologie des Gebietes Radiologie

2012 – 2015          Chefarzt Radiologie Chirurgische Klinik Dr. Rinecker, München
                            (246 Betten)

2014 – 2015          Zusätzlich Übernahme der Röntgenabteilung der Internistischen       Klinik Dr.          Müller (125 Betten)

2014                     Erteilung der Lehrbefugnis an der Ludwig-Maximilians-Universität     München für     das Fachgebet Radiologie

2016 – 2016          Leiter Radiologie Isar Medizin Zentrum GmbH MVZ
                            Isar Klinikum (145 Betten, Klinik der Maximalversorgung)

2016                     Bestellung zum außerplanmäßigen Professor (LMU)

Seit 2017              Chefarzt für Diagnostische und Interventionelle Radiologie
                            Artemed Klinikum München Süd (246 Betten)

Seit 2017              Zusätzliche Übernahme der radiologischen Versorgung der Abteilung           Radiologie, Internistisches Klinikum München Süd (120 Betten)

Deutsche Röntgengesellschaft

            Vorsitzender AG Thoraxdiagnostik

Deutsche Gesellschaft für Kardiologie (DGK)

Deutsche Gesellschaft für Pneumologie (DGP)

European Society of Cardiac Radiology (ESCR)

European Society of Thoracic Radiology (ESTI)

European Respiratory Society (ERS)

Chair of the Imaging Group: 2009-2012

Secretary of the Imaging Group: 2013-2015

Associate Editor der Fachzeitschrift Echocardiography

Associate Editor der Fachzeitschrift Pulmonology

Gutachter für zahlreiche nationale und internationale Fachzeitschriften

Ley S, Ley-Zaporozhan J.

[Imaging of Mediastinal Tumors].

Zentralbl Chir. 2021 Feb;146(1):88-104. doi: 10.1055/a-1171-2766

Ley S, Fidler L, Schenk H, Durand M, Marras T, Paul N, Shapera S, Mittoo S.

Low dose computed tomography of the lung for detection and grading of interstitial lung disease: A systematic simulation study.

Pulmonology. 20 21 Jan-Feb;27(1):14-25. doi: 10.1016/j.pulmoe.2020.06.004

Ley S, Ley-Zaporozhan J.

Novelties in imaging in pulmonary fibrosis and nodules. A narrative review.

Pulmonology. 2020 Jan-Feb;26(1):39-44

Ley S, Estebesova B.

Thoracic imaging: course report.

Breathe (Sheff). 2019 Mar;15(1):4-6

Ley S, Ley-Zaporozhan J

Imaging in vascular diseases of the lung.

Curr Opin Pulm Med. 2016 Sep;22(5):522-6

Ley S, Ambrosino N, Mishra DR.

Thoracic imaging: course report.

Breathe (Sheff). 2016 Mar;12(1):9-10

Ley S, Ley-Zaporozhan J

[Cardiac and vascular malformations].

Radiologe. 2015 Jul;55(7):570-9

Ley S

Lung imaging.

Eur Respir Rev. 2015 Jun;24(136):240-5

Ley S

Imaging pulmonary arterial thromboembolism: challenges and opportunities.

Magn Reson Imaging Clin N Am. 2015 May;23(2):261-71

Rengier F, Delles M, Eichhorn J, Azad YJ, von Tengg-Kobligk H, Ley-Zaporozhan J, Dillmann R, Kauczor HU, Unterhinninghofen R, Ley S.

Noninvasive 4D pressure difference mapping derived from 4D flow MRI in patients with repaired aortic coarctation: comparison with young healthy volunteers.

Int J Cardiovasc Imaging. 2015 Apr;31(4):823-30

Owsijewitsch M, Ley-Zaporozhan J, Kuhnigk JM, Kopp-Schneider A, Eberhardt R, Eichinger M, Heussel CP, Kauczor HU, Ley S.

Quantitative Emphysema Distribution in Anatomic and Non-anatomic Lung Regions.

COPD. 2015 Jun;12(3):257-66

Ley S, Ley-Zaporozhan J, Gorenflo M, Arnold R

Mid-Term Follow-Up after Arterial Switch Operation for Complete Transposition of the Great Arteries

Journal of Cardiology and Therapeutics 2015 Mar; 3(1) 16-24

DOI: http://dx.doi.org/10.12970/2311-052X.2015.03.01.2

Ley-Zaporozhan J, Ley S

[HRCT technique with low-dose protocols for interstitial lung diseases].

Radiologe. 2014 Dec;54(12):1153-8

Rengier F, Delles M, Eichhorn J, Azad YJ, von Tengg-Kobligk H, Ley-Zaporozhan J, Dillmann R, Kauczor HU, Unterhinninghofen R, Ley S

Noninvasive pressure difference mapping derived from 4D flow MRI in patients with unrepaired and repaired aortic coarctation.

Cardiovasc Diagn Ther. 2014 Apr;4(2):97-103

Ley S, Fink C, Risse F, Ehlken N, Fischer C, Ley-Zaporozhan J, Kauczor HU, Klose H, Gruenig E.

Magnetic resonance imaging to assess the effect of exercise training on pulmonary perfusion and blood flow in patients with pulmonary hypertension.

Eur Radiol. 2013 Feb;23(2):324-31

Ley S, Ley-Zaporozhan J, Pitton MB, Schneider J, Wirth GM, Mayer E, Düber C, Kreitner KF.

Diagnostic performance of state-of-the-art imaging techniques for morphological assessment of vascular abnormalities in patients with chronic thromboembolic pulmonary hypertension (CTEPH).

Eur Radiol. 2012 Mar;22(3):607-16

James SH, Rachel W, Wintersperger BJ, Jimenez-Juan L, Deva D, Crean AM , Nguyen E, Paul NS, Ley S.

Accuracy of right (RV) and left ventricular (LV) functional assessment by short-axis vs. axial cine SSFP MR imaging: intrapatient correlation with main pulmonary artery and ascending aorta phase-contrast flow measurements

Can Assoc Radiol J. 2013 Aug;64(3):213-219

Giesel FL, Kratochwil C, Mehndiratta A, Wulfert S, Moltz JH, Zechmann CM, Kauczor HU, Haberkorn U, Ley S.

Comparison of neuroendocrine tumor detection and characterization using DOTATOC-PET in correlation with contrast enhanced CT and delayed contrast enhanced MRI.

Eur J Radiol. 2012 Oct;81(10):2820-5

Weber TF, von Tengg-Kobligk H, Kopp-Schneider A, Ley-Zaporozhan J, Kauczor HU, Ley S.

High-resolution phase-contrast MRI of aortic and pulmonary blood flow during rest and physical exercise using a MRI compatible bicycle ergometer.

Eur J Radiol. 2011 Oct;80(1):103-8

Ley-Zaporozhan J, Molinari F, Risse F, Puderbach M, Schenk JP, Kopp-Schneider A, Kauczor HU, Ley S

Repeatability and Reproducibility of Quantitative Whole-lung Perfusion Magnetic Resonance Imaging.

J Thorac Imaging. 2011 Aug;26(3):230-9

Ley S, Ley-Zaporozhan J

Pulmonary perfusion imaging using MRI: clinical application

Insight Imaging 2012 Feb;3(1):61-71

Ley S, Ley-Zaporozhan J, Pitton MB, Schneider J, Wirth GM, Mayer E, Düber C, Kreitner KF

Diagnostic performance of state-of-the-art imaging techniques for morphological assessment of vascular abnormalities in patients with chronic thromboembolic pulmonary hypertension (CTEPH).

Eur Radiol. 2012 Mar;22(3):607-16

Hochhegger B, Ley-Zaporozhan J, Marchiori E, Irion K, Soares Souza A Jr, Moreira J, Kauczor HU, Ley S.

Magnetic resonance imaging findings in acute pulmonary embolism.

Br J Radiol. 2011 Mar;84(999):282-7

Ley S, Ley-Zaporozhan J, Günther P, Witt O, Schenk JP.

Neuroblastoma Imaging

RöFo 2011 Mar;183(3):217-225

Ley S, Grünig E, van Beek E, Wild J.

CT and MRI of pulmonary hypertension – pulmonary vessels and right ventricle

JMRI 2010 Dec;32(6):1313-24

Kauczor HU, Ley S.

Thoracic magnetic resonance imaging 1985 to 2010

J Thorac Imaging. 2010 Feb;25(1):34-8.

Ley S*, Loukanov T*, Ley-Zaporozhan J, Springer W, Sebening C, Sommerburg O, Hagl S, Gorenflo M.

Long-term outcome after external tracheal stabilization under cardiopulmonary bypass due to congenital tracheal instability

Annals of Thoracic Surgery. 2010 Mar;89(3):918-925

Kauczor HU, Ley-Zaporozhan J, Ley S.

Imaging of pulmonary pathologies: focus on magnetic resonance imaging.

Proc Am Thorac Soc. 2009 Aug 15;6(5):458-63

Ley S, Ley-Zaporozhan J, Schenk JP.       
Whole-body MRI in the pediatric patient.    
Eur J Radiol. 2009 Jun;70(3):442-51.

von Tengg-Kobligk H., Ley-Zaporozhan J, Henninger V, Gruenberg K, Giesel FL, Böckler D, Krummenauer F, Kauczor HU, Ley S.

Intraindividual assessment of the thoracic aorta using contrast and non contrast-enhanced MR angiography
Rofo, 2009 Mar;181(3):230-6

Ley S, Unterhinninghofen R, Ley-Zaporozhan J, Schenk JP, Kauczor HU, Szabo G.
Validation of magnetic resonance phase-contrast flow measurements in the main pulmonary artery and aorta using perivascular ultrasound in a large animal model.
Invest Radiol. 2008 Jun;43(6):421-6.

Grünig E, Ley S.

Echocardiography and magnetic resonance imaging in patients suffering from pulmonary arterial hypertension.
Dtsch Med Wochenschr. 2008 Oct;133 Suppl 6:S173-5

von Tengg-Kobligk H, Weber TF, Rengier F, Kotelis D, Geisbüsch P, Böckler D, Schumacher H, Ley S.       Imaging modalities for the thoracic aorta.

J Cardiovasc Surg (Torino). 2008 Aug;49(4):429-47

Ley S, Kauczor HU.
MR imaging/magnetic resonance angiography of the pulmonary arteries and pulmonary thromboembolic disease.
Magn Reson Imaging Clin N Am. 2008 May;16(2):263-73. Review.

Ley-Zaporozhan J, Kreitner KF, Unterhinninghofen R, Helm E, Puderbach M, Schenk JP, Deshpande V, Krummenauer F, Szabo G, Kauczor HU, Ley S.
Assessment of thoracic aortic dimensions in an experimental setting: comparison of different unenhanced magnetic resonance angiography techniques with electrocardiogram-gated computed tomography angiography for possible application in the pediatric population.
Invest Radiol. 2008 Mar;43(3):179-86.

Arnold R*, Ley S* (*equal contribution), Ley-Zaporozhan J, Eichhorn J, Schenk JP, Ulmer H, Kauczor HU.
Visualization of coronary arteries in patients after childhood Kawasaki syndrome: value of multidetector CT and MR imaging in comparison to conventional coronary catheterization.
Pediatr Radiol. 2007 Oct;37(10):998-1006.

Ley-Zaporozhan*J, Ley S* (*equal contribution), Weinheimer O, Iliyushenko S, Erdugan S, Eberhardt R, Fuxa A, Mews J, Kauczor HU.
Quantitative analysis of emphysema in 3D using MDCT: influence of different reconstruction algorithms.
Eur J Radiol. 2008 Feb;65(2):228-34.

Eichhorn JG, Ley S.

Congenital abnormalities of the aorta in children and adolescents.

Radiologe. 2007 Nov;47(11):974-81. Review. German.

Ley S, Puderbach M, Risse F, Ley-Zaporozhan J, Eichinger M, Takenaka D, Kauczor HU, Bock M.
Impact of oxygen inhalation on the pulmonary circulation: assessment by magnetic resonance (MR)-perfusion and MR-flow measurements.
Invest Radiol. 2007 May;42(5):283-90.

Ley S, Eichhorn J, Ley-Zaporozhan J, Ulmer H, Schenk JP, Kauczor HU, Arnold R.
Evaluation of aortic regurgitation in congenital heart disease: value of MR imaging in comparison to echocardiography.
Pediatr Radiol. 2007 May;37(5):426-36.

Ley S, Mereles D, Puderbach M, Gruenig E, Schöck H, Eichinger M, Ley-Zaporozhan J, Fink C, Kauczor HU.
Value of MR phase-contrast flow measurements for functional assessment of pulmonary arterial hypertension.
Eur Radiol. 2007 Jul;17(7):1892-7.

Ley S, Ley-Zaporozhan J, Unterhinninghofen R, Saito Y, Fabel-Schulte M, Weinheimer O, Schenk JP, Szabo G, Kauczor HU.
Investigation of retrospective respiratory gating techniques for acquisition of thin-slice 4D-Multidetector-computed Tomography (MDCT) of the lung: Feasibility study in a large animal model.
Exp Lung Res. 2006 Oct;32(9):395-412.

Ley S, Mereles D, Risse F, Grünig E, Ley-Zaporozhan J, Tecer Z, Puderbach M, Fink C, Kauczor HU.
Quantitative 3D pulmonary MR-perfusion in patients with pulmonary arterial hypertension: correlation with invasive pressure measurements.
Eur J Radiol. 2007 Feb;61(2):251-5.

Ley S, Ley-Zaporozhan J, Kreitner KF, Iliyushenko S, Puderbach M, Hosch W, Wenz H, Schenk JP, Kauczor HU.
MR flow measurements for assessment of the pulmonary, systemic and bronchosystemic circulation: impact of different ECG gating methods and breathing schema.
Eur J Radiol. 2007 Jan;61(1):124-9. Epub 2006 Oct 4.

Ley S, Fink C, Puderbach M, Zaporozhan J, Plathow C, Eichinger M, Hosch W, Kreitner KF, Kauczor HU.
MRI Measurement of the hemodynamics of the pulmonary and systemic arterial circulation: influence of breathing maneuvers.
AJR Am J Roentgenol. 2006 Aug;187(2):439-44.

Ley S, Zaporozhan J, Arnold R, Eichhorn J, Schenk JP, Ulmer H, Kreitner KF, Kauczor HU.
Preoperative assessment and follow-up of congenital abnormalities of the pulmonary arteries using CT and MRI.
Eur Radiol. 2007 Jan;17(1):151-62.

Ley S, Fink C, Zaporozhan J, Borst MM, Meyer FJ, Puderbach M, Eichinger M, Plathow C, Grünig E, Kreitner KF, Kauczor HU.
Value of high spatial and high temporal resolution magnetic resonance angiography for differentiation between idiopathic and thromboembolic pulmonary hypertension: initial results.
Eur Radiol. 2005 Nov;15(11):2256-63.

Plathow C*, Ley S* (*equal contribution), Zaporozhan J, Schöbinger M, Gruenig E, Puderbach M, Eichinger M, Meinzer HP, Zuna I, Kauczor HU.
Assessment of reproducibility and stability of different breath-hold maneuvres by dynamic MRI: comparison between healthy adults and patients with pulmonary hypertension.
Eur Radiol. 2006 Jan;16(1):173-9.

Ley S, Puderbach M, Fink C, Eichinger M, Plathow C, Teiner S, Wiebel M, Müller FM, Kauczor HU.
Assessment of hemodynamic changes in the systemic and pulmonary arterial circulation in patients with cystic fibrosis using phase-contrast MRI.
Eur Radiol. 2005 Aug;15(8):1575-80.

Ley S, Zaporozhan J, Morbach A, Eberle B, Gast KK, Heussel CP, Biedermann A, Mayer E, Schmiedeskamp J, Stepniak A, Schreiber WG, Kauczor HU.
Functional evaluation of emphysema using diffusion-weighted 3Helium-magnetic resonance imaging, high-resolution computed tomography, and lung function tests.
Invest Radiol. 2004 Jul;39(7):427-34.

Ley S, Fink C, Puderbach M, Plathow C, Risse F, Kreitner KF, Kauczor HU.
[Contrast-enhanced 3D MR perfusion of the lung: application of parallel imaging technique in healthy subjects]
Rofo. 2004 Mar;176(3):330-4. German.

Ley S, Kreitner KF, Fink C, Heussel CP, Borst MM, Kauczor HU.
Assessment of pulmonary hypertension by CT and MR imaging.
Eur Radiol. 2004 Mar;14(3):359-68. Review.

Ley S, Kramm T, Kauczor HU, Mayer E, Heussel CP, Thelen M, Kreitner KF.
[Pre- and postoperative assessment of hemodynamics in patients with chronic thromboembolic pulmonary hypertension by MR techniques]
Rofo. 2003 Dec;175(12):1647-54. German.

Ley S, Kauczor HU, Heussel CP, Kramm T, Mayer E, Thelen M, Kreitner KF.
Value of contrast-enhanced MR angiography and helical CT angiography in chronic thromboembolic pulmonary hypertension.
Eur Radiol. 2003 Oct;13(10):2365-71.

Ley S, Kreitner KF, Morgenstern I, Thelen M, Kauczor HU.
Bronchopulmonary shunts in patients with chronic thromboembolic pulmonary hypertension: evaluation with helical CT and MR imaging.
AJR Am J Roentgenol. 2002 Nov;179(5):1209-15.

Ley S, Mayer D, Brook BS, van Beek EJ, Heussel CP, Rinck D, Hose R, Markstaller K, Kauczor HU.
Radiological imaging as the basis for a simulation software of ventilation in the tracheo-bronchial tree.
Eur Radiol. 2002 Sep;12(9):2218-28.